Successful respiratory immunization with dry powder live-attenuated measles virus vaccine in rhesus macaques.

Mass immunization of children in Iran with live attenuated Sugiyama measles virus adapted to calf kidney cell cultures

Efficacy and safety of live attenuated Sugiyama strain of measles virus in mass immunization of children in rural regions of Iran

Evaluation of Measles Vaccine Virus as a Vector to Deliver Respiratory Syncytial Virus Fusion Protein or Epstein-Barr Virus Glycoprotein gp350

Live attenuated recombinant measles vaccine virus (MV) Edmonston-Zagreb (EZ) strain was evaluated as a viral vector to express the ectodomains of fusion protein of respiratory syncytial virus (RSV F) or glycoprotein 350 of Epstein-Barr virus (EBV gp350) as candidate vaccines for prophylaxis of RSV and EBV. The glycoprotein gene was inserted at the 1(st) or the 3(rd) position of the measles viru...

Protective immunity in macaques vaccinated with live attenuated, recombinant, and subunit measles vaccines in the presence of passively acquired antibodies.

The presence of maternal antibodies is one of the main causes of measles vaccine failure. To evaluate the interference of passively acquired antibodies with vaccine efficacy, macaques (n = 16) were vaccinated with live attenuated measles vaccine in the presence or absence of passively acquired measles virus-specific monkey serum antibodies. As little as 0.1 IU of virus-neutralizing antibody/mL ...

Safer Vaccines and Antibiotics Manufactured through Use of Near- Critical or Supercritical Fluids

Near-critical and supercritical fluids have been used successfully in the manufacture of vaccine, antibody and antibiotic microparticles by Carbon-dioxide Assisted Nebulization with a Bubble Dryer ® (CAN-BD). In CAN-BD two fluid streams, a drug, antibody, or vaccine solution or suspension, and supercritical or near-critical CO2, are intimately mixed in a low dead volume tee. These mixed fluid s...